Parkinson’s disease (PD) destroys the nerve cells generates the structure of dopamine in the brain. A person with this type of disease usually undergoes relentless deficiency in dopamine. In Lewy bodies, synuclein can form unsolvable fibrils. Lewy bodies are the pathological characteristic of PD in nigrostriatal system. During the course of the disease, people affected may experience difficulty in speech and movements. Others may experience sleep problems, hopelessness, or having a hard time swallowing and chewing.

PD usually starts in women and men at age 60, or even earlier. It is more frequently occurs in men than women. Despite the fact that people on many countries are affected by PD, to some extent it is widespread in whites than Asians and Africa Americans.

At present, there are four theories on the origin/etiology of Parkinson’s disease. PD may be the outcome of environmental factors which includes living in countryside, contact with heavy metals, and drinking on well water. Potassium cyanide, methyl alcohol, carbon disulphide, manganese ore dust, and carbon monoxide poisoning also add to this factor. In the course of study and investigation, it is concluded that no one of these agents possibly the only cause of PD. The detection should offer some soothe to family members of PD victims who fear for their own future health. Probable environmental causes should be the focal point for every study.

MPTP, a type of narcotics, has been recognized to devastate brain parts. Another possible cause of PD that has been recommended was the infectious disease. There was an epidemic during the early 1900’s that caused to people experience severe insomnia and stupor. The infection was usually known as encephalitis lethargic or sleeping sickness. Some signs and symptoms of PD were experienced by most of the victims. Some scientists consider accelerated aging as a factor for Parkinson’s disease. The ability of the brain to produce dopamine decreases and the outcome of this was the symptoms of PD.

Other researchers assume that PD is hereditary and has a cause. PD was experienced by lots of families in numerous generations. This cluster of victims tends to follow either the mother or the father side of the family. According to many studies, PD is two times more likely to build up on the first-degree relatives of the victims of this disease compared to relatives with no history of the said disease. The gene that is located on chromosome 4 was recognized by the researchers as an abnormal gene and documented as the basis of PD’s symptoms. Still, some researchers believed that PD results in an arrangement of genetic and environmental influences, because of the reason that some patients have no hereditary link and it does not exist in the family.

A large number of researches are being done to discover innovative ways to minimize PD’S symptoms and maximize the amount of dopamine in the brain. Despite the fact that Parkinson’s disease is a progressive, deteriorative, and persistent disease, fresh discoveries are made to assist us in finding a cure. This makes it unsophisticated for PD patients to do their role on daily scenarios.